陈丽建 副研究员/硕导
地址: 江苏省无锡市蠡湖大道1800号,江南大学食品学院,分析食品安全学研究所
邮编:214122
办公室: 协同创新中心A241
电话:0510-85916732
E-mail:chenlijian@jiangnan.edu.cn
研究方向
(1)光响应功能纳米材料的制备及其传感/成像应用
(2)食品功能成分和危害物的分析检测;
(3)食品有害成分的迁移示踪/毒性评价和抑制研究;
学习工作经历
2022.6至今,江南大学食品学院,副研究员
2020.4-2022.5 江南大学食品学院,助理研究员
2017.12-2020.4 江南大学食品学院,博士后,导师:严秀平教授
2017.7-2017.12 青岛大学转化医学研究院,讲师
2014.9-2017.6 南开大学化学学院,博士,导师:严秀平教授
2011.9-2014.6 山东农业大学化学与材料科学学院,硕士,导师:艾仕云教授
2007.9-2011.6 山东农业大学化学与材料科学学院,本科
科研项目
主持国家自然科学基金青年项目“生物膜伪装近红外有机长余辉纳米探针用于炎症与动脉粥样硬化易损斑块成像”(21804057)
主持江苏省自然科学基金青年项目“仿生近红外有机长余辉纳米探针的制备及其光学成像研究”(BK20180584)
主持中国博士后基金一等面上项目“白细胞膜包被长余辉纳米探针用于炎症靶向成像与治疗”(2018M630509)
获中国博士后创新人才支持计划资助“多功能近红外长余辉纳米探针用于荧光成像检测食源性致病细菌”(BX20180130)
主持江南大学基本科研计划青年基金“基于光响应纳米材料的高效富集型微针贴片用于生鲜食品新鲜度的快速灵敏检测”(JUSRP121005)
代表性论文
(1) Dong-Mei Zhou, Li-Jian Chen*, Xu Zhao, Li-Xia Yan, Xiu-Ping Yan*. Persistent Production of Multiple Active Species with Copper Doped Zinc Gallate Nanoparticles for Light-Independent Photocatalytic Degradation of Organic Pollutants. Journal of Colloid and Interface Science. 2024, 668, 540-550.
(2) Ting-Jiao Shi, Dong-Hui Wang, Xu Zhao, Li-Jian Chen* and Xiu-Ping Yan*. Afterglow Performance of Phenylenevinylene-Based Semiconducting Polymer Nanoparticles Doped with Photosensitizers Containing Electron-Withdrawing Group. Chemistry - A European Journal. 2024, 30, e202400950.
(3) Jiang-Yue Wang, Li-Jian Chen*, Xu Zhao, Xiu-Ping Yan. Silk fibroin-based colorimetric microneedle patch for rapid detection of spoilage in packaged salmon samples. Food Chemistry. 2023, 406, 135039.
(4) Xu Zhao, Ting-Jiao Shi, Yao-Yao Liu, and Li-Jian Chen*. Porphyrinic Metal−Organic Framework-Loaded Polycaprolactone Composite Films with a High Photodynamic Antibacterial Activity for the Preservation of Fresh-Cut Apples. ACS Applied Polymer Materials. 2023, 5, 1, 560-566.
(5) Li-Jian Chen, Xu Zhao, Xiu-Ping Yan. Porphyrinic Metal-Organic Frameworks for Biological Applications. Advanced Sensor and Energy Materials, 2023, 2, 100045.
(6). Jia-Hua Gong, Li-Jian Chen,* Xu Zhao, and Xiu-Ping Yan*. Persistent Production of Reactive Oxygen Species with Zn2GeO4:Cu Nanorod-Loaded Microneedles for Methicillin-Resistant Staphylococcus Aureus Infectious Wound Healing. ACS Applied Materials & Interfaces. 2022, 14, 17142-17152.
(7). Li-Jian Chen, Yao-Yao Liu, Xu Zhao, and Xiu-Ping Yan*. Vancomycin-Functionalized Porphyrinic Metal-Organic Framework PCN-224 with Enhanced Antibacterial Activity against Staphylococcus Aureus. Chemistry-An Asian Journal, 2021, 16, 2022-2026.
(8). Yao-Yao Liu, Li-Jian Chen,* Xu Zhao, and Xiu-Ping Yan* Effect of Topology on Photodynamic Sterilization of Porphyrinic Metal-Organic Frameworks. Chemistry - A European Journal 2021, 27, 10151-10159.
(9). Li-Jian Chen, Xu Zhao, Yao-Yao Liu, and Xiu-Ping Yan.* Macrophage Membrane Coated Persistent Luminescence Nanoparticle@MOF-Derived Mesoporous Carbon Core–Shell Nanocomposites for Autofluorescence-Free Imaging-Guided Chemotherapy. Journal of Materials Chemistry B, 2020, 8, 8071-8083.
(10). Li-Jian Chen, Xu Zhao, and Xiu-Ping Yan.* Cell-Penetrating Peptide-Functionalized Persistent Luminescence Nanoparticles for Tracking J774A.1 Macrophages Homing to Inflamed Tissues. ACS Applied Materials & Interfaces, 2019, 11, 19894-19901.
(11). Chen, Li-Jian; Yang, Cheng-Xiong; Yan, Xiu-Ping*: Liposome-Coated Persistent Luminescence Nanoparticles as Luminescence Trackable Drug Carrier for Chemotherapy. Analytical Chemistry, 2017, 89(13): 6936-6939.
(12). Chen, Li-Jian; Sun, Shao-Kai; Wang, Yong; Yang, Cheng-Xiong; Wu, Shu-Qi; Yan, Xiu-Ping*: Activatable Multifunctional Persistent Luminescence Nanoparticle/Copper Sulfide Nanoprobe for in Vivo Luminescence Imaging Guided Photothermal Therapy. ACS Applied Materials & Interfaces, 2016, 8(48): 32667-32674.
(13). Chen, Lijian; Sun, Kaifang; Li, Peipei; Fan, Xianzhong; Sun, Jianchao; Ai, Shiyun*: DNA-Enhanced Peroxidase-Like Activity of Layered Double Hydroxide Nanosheets and Applications in H2O2 and Glucose Sensing, Nanoscale, 2013, 5(22): 10982-10988.
(14). Chen, Lijian; Wu, Na; Sun, Bing; Su, Haichao; Ai, Shiyun*: Colorimetric Detection of Peroxynitrite-Induced DNA Damage Using Gold Nanoparticles, and on The Scavenging Effects of Antioxidants. Microchimica Acta, 2013, 180(7-8): 573-580.
(15). Chen, Lijian; Sun, Bing; Wang, Xindong; Qiao, Fengmin; Ai, Shiyun*: 2D Ultrathin Nanosheets of Co-Al Layered Double Hydroxides Prepared in L-asparagine Solution: Enhanced Peroxidase-Like Activity and Colorimetric Detection of Glucose. Journal of Materials Chemistry B, 2013, 1(17): 2268-2274.
(16). Chen, Lijian; Wang, Nan; Wang, Xindong; Ai, Shiyun*: Protein-Directed in Situ Synthesis of Platinum Nanoparticles with Superior Peroxidase-Like Activity, and Their Use for Photometric Determination of Hydrogen Peroxide. Microchimica Acta, 2013, 180(15-16): 1517-1522.
专利
1. 陈丽建,严秀平,王江悦,龚嘉华. 一种可变色水凝胶微针贴片、制备方法及其应用, ZL 202111537252.4;
2. 陈丽建,严秀平. 一种可近红外光余辉成像示踪的纳米药物载体及其制备,ZL201911171581.4;
3. 陈丽建,严秀平,龚嘉华,王江悦,刘瑶瑶. 一种可余辉光监测缓释抗菌的锗酸锌基质纳米材料及其制备方法,ZL202110633407.8。
4. 陈丽建,严秀平,王江悦,刘瑶瑶,龚嘉华. 光敏抗菌的改性卟啉金属有机骨架材料及其制备方法,ZL202110622769.7。
5. 陈丽建,严秀平,刘瑶瑶,王江悦,龚嘉华. 一种可降解抗菌膜及其制备方法,ZL202110670399.4。
获奖
1. 2020年度中国博士后创新人才支持计划优秀创新成果;
2. 2019年度中国分析测试协会科学技术奖-CAIA特等奖(排名5)。
3. 2023年“科创无锡、创响无锡”创新创业大赛市级优秀奖(排名1)